Assoc Prof Dr. Jing Ruan | Materials Science | Editorial Board Member
Shanghai Jiao Tong University School of Medicine | China
Dr. Jing Ruan is an Associate Professor in the Department of Ophthalmology at the Shanghai Jiao Tong University School of Medicine and the Affiliated Ninth People’s Hospital. She earned her Ph.D. in Biomedical Engineering from Shanghai Jiao Tong University and completed earlier degrees in Materials Science & Engineering (B.S.) and Applied Chemistry (M.S.). Her research trajectory spans materials science, biomedical engineering, ophthalmology, and translational nanomedicine. Prior to her academic appointment, she contributed to drug discovery research at Lilly China Research and Development Center, strengthening her foundation in therapeutic innovations. Dr. Ruan’s research focuses on the design of implantable biomaterials and the molecular mechanisms underlying cellular responses. She is internationally recognized for her work in ocular oncology, particularly the epigenetic and pathogenic processes driving melanoma progression. Her interdisciplinary expertise extends to nanotechnology-based targeted cancer therapies, including gene nanocarriers, multimodal theranostic nanoprobes, and nano–immune adjuvants. Over the past five years, she has authored numerous high-impact publications in Acta Biomaterialia, Nano Today, Oncogene, Clinical and Translational Medicine, Bioactive Materials, and Advanced Science, reflecting significant contributions to cancer therapeutics, biomimetic scaffolds, nanotoxicology, and photodynamic therapy. Her collective body of work exceeds dozens of peer-reviewed papers, many of which involve collaborations with leading scientists such as Kam W. Leong, X.J. Loh, and X. Fan, underscoring her strong interdisciplinary and international research partnerships. Her research excellence has been recognized through multiple prestigious awards, including the Pujiang Award (2021), Rising Star Award (2017), and Outstanding Doctoral Dissertation Award (2016). Earlier distinctions such as the Young Artist Award and the First Ruth Mulan Chu Chao Scholarship highlight her longstanding academic merit.
Profiles: Scopus
Featured Publications
1. Ma, Y., Lin, H., Wang, P., Yang, H., Yu, J., Tian, H., Li, T., Ge, S., Wang, Y., Jia, R., Leong, K. W., & Ruan, J. (2022). A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma. Acta Biomaterialia.
2. Ruan, J., Li, F., Tian, H., Yu, J., Deng, H., Ge, S., & Leong, K. W. (2022). A cascade FRET photosensitizer that enhances photodynamic therapy for ocular melanoma. Nano Today, 47, 101684.
3. Zhuang, A., Chai, P., Wang, S., Zuo, S., Yu, J., Jia, S., Ge, S., Jia, R., Zhou, Y., Shi, W., Xu, X., Ruan, J., & Fan, X. (2022). Metformin promotes histone deacetylation of optineurin and suppresses tumour growth through autophagy inhibition in ocular melanoma. Clinical and Translational Medicine, 12(1), e660.
4. Gu, X., Zhuang, A., Yu, J., Chai, P., Jia, R., & Ruan, J. (2022). Phase separation drives tumor pathogenesis and evolution: All roads lead to Rome. Oncogene, 41(11), 1527–1535.
5. Tian, H., Shi, H., Yu, J., Ge, S., & Ruan, J. (2022). Biophysics role and biomimetic culture systems of ECM stiffness in cancer EMT. Global Challenges, 6(6), 2100094.
