Dr. Sotiri Stathakis | Medicine and Dentistry | Best Researcher Award

Mary Bird Perkins Cancer Center | United States

Dr. Sotirios Stathakis is an accomplished medical physicist with extensive experience in radiation oncology, advanced treatment planning, and patient safety in cancer care. Currently serving as the Chief of Physics at Mary Bird Perkins Cancer Center and Adjunct Professor at Louisiana State University, he has established himself as a leader in both clinical and academic domains. His work bridges fundamental research and real-world clinical application, focusing on improving the accuracy, efficiency, and safety of radiotherapy treatments. With a career spanning over two decades, Dr. Stathakis has played a pivotal role in advancing technologies such as intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), Monte Carlo simulations, and adaptive radiotherapy. He has supervised graduate students, medical residents, and postdoctoral fellows, contributing to the development of the next generation of medical physicists. Dr. Stathakis is internationally recognized for his innovative contributions to medical physics, publishing widely in peer-reviewed journals and presenting at global conferences. His leadership in quality assurance (QA) protocols, radiotherapy safety standards, and patient-centered innovations has earned him professional recognition as a Fellow of the American Association of Physicists in Medicine (AAPM). He continues to expand his research by integrating artificial intelligence, patient education, and wearable technology into cancer care.

Professional Profile

Scopus | ORCID

Education

Dr. Sotirios Stathakis has a strong academic background rooted in physics and medical physics, which forms the foundation of his distinguished career in cancer treatment and research. He began his academic journey with a Bachelor of Science in Physics from the University of Waterloo, Canada, where he developed a strong foundation in core physical sciences and problem-solving skills. Driven by an interest in applying physics to medicine, he pursued a Master of Science in Medical Physics at the University of Aberdeen, United Kingdom. Here, he received specialized training in radiological sciences, medical imaging, and radiotherapy applications, which fueled his passion for research in patient care. His academic progression culminated in a Ph.D. in Medical Physics from the University of Patras, Greece, where his doctoral work focused on advanced radiation dosimetry and optimization of treatment planning systems. His doctoral training allowed him to explore Monte Carlo simulations and radiation safety protocols, which later became key aspects of his professional contributions. This comprehensive education, spanning North America and Europe, equipped him with a unique global perspective and multidisciplinary expertise. It also prepared him to integrate clinical practice with research, ultimately shaping his career as a recognized leader in medical physics and radiation oncology.

Professional Experience

Dr. Sotirios Stathakis has accumulated diverse professional experience that reflects his dual commitment to academic research and clinical application. He began his career in Europe, contributing to medical physics research before moving to the United States, where he established himself in leading academic and clinical institutions. At the University of Texas Health Science Center San Antonio (UTHSA), he served as a Professor and Medical Physicist, taking on responsibilities that included treatment planning, clinical implementation of new radiotherapy techniques, and the supervision of graduate students and medical residents. His academic contributions included teaching advanced courses in radiation oncology physics and mentoring Ph.D. dissertations. He later transitioned to his current role as Chief of Physics at Mary Bird Perkins Cancer Center, where he oversees medical physics operations across multiple oncology centers. In this role, he leads a team of physicists and ensures the safe and effective delivery of radiation treatments to cancer patients. His position as Adjunct Professor at Louisiana State University complements his clinical work, as he continues to teach and mentor the next generation of medical physicists. Throughout his career, Dr. Stathakis has balanced leadership, clinical service, and research, contributing to advancements in both patient care and academic knowledge.

Research Interests

Dr. Sotirios Stathakis’s research interests lie at the intersection of clinical innovation, radiation therapy optimization, and patient-centered approaches. A central focus of his research is the improvement of treatment planning systems, particularly through advanced modeling such as Monte Carlo simulations, which enhance accuracy in dose calculations. He has contributed to the development and refinement of quality assurance (QA) protocols, ensuring precision in intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). Another important area of his research includes studying the secondary cancer risks associated with radiotherapy, providing valuable insights into long-term patient safety. Dr. Stathakis is also exploring the role of artificial intelligence (AI) in radiotherapy, particularly for dose prediction and workflow optimization, which has the potential to revolutionize clinical practices. In recent years, he has expanded his focus to include patient-centered technologies, such as wearable monitoring devices and virtual reality tools that improve patient education, engagement, and treatment compliance. His interdisciplinary approach combines physics, engineering, computer science, and clinical oncology, creating innovative solutions to complex healthcare challenges. By bridging these fields, Dr. Stathakis continues to advance the standards of radiotherapy, contributing to safer, more effective, and personalized cancer treatments.

Research Skills

Dr. Sotirios Stathakis possesses a broad range of research skills that span computational modeling, experimental validation, clinical trial design, and academic mentoring. His expertise in Monte Carlo simulations allows him to perform highly accurate radiation dose calculations, a critical aspect of treatment planning and safety assessment in radiation oncology. He is also highly skilled in advanced quality assurance techniques, particularly for IMRT and VMAT, ensuring reliable and precise delivery of radiation therapy. Dr. Stathakis is proficient in using and commissioning treatment planning systems and linear accelerators, applying both theoretical and practical approaches to improve clinical workflows. His research methodology incorporates statistical analysis, machine learning, and artificial intelligence, enabling him to address complex problems in treatment optimization and patient safety. Beyond technical skills, he excels in collaborative project management, coordinating interdisciplinary teams across physics, medicine, and engineering. His experience extends to academic publishing, peer review, and conference presentations, reflecting his ability to effectively disseminate scientific findings. As a mentor and educator, he has guided Ph.D. students and medical residents in developing independent research projects, further demonstrating his leadership in research environments. Collectively, these skills highlight his ability to translate advanced scientific concepts into practical innovations that benefit cancer patients worldwide.

Awards and Honors

Throughout his career, Dr. Sotirios Stathakis has received numerous awards and honors in recognition of his academic excellence, clinical leadership, and professional service. One of the most prestigious distinctions in his career is being named a Fellow of the American Association of Physicists in Medicine (AAPM), a recognition reserved for members who have made significant contributions to the advancement of medical physics. He is also board-certified in Therapeutic Radiologic Physics by the American Board of Radiology (ABR), underscoring his professional expertise and credibility in clinical practice. His academic work has been acknowledged through invitations to present at leading international conferences, including those organized by IEEE, AAPM, and ESTRO, where he has shared groundbreaking findings on radiotherapy optimization and quality assurance. In addition, Dr. Stathakis has served as a peer reviewer for high-impact journals such as the Journal of Applied Clinical Medical Physics (JACMP), further highlighting his standing in the scientific community. He has also been recognized by institutions where he has taught and worked, receiving commendations for excellence in mentorship and clinical service. These honors reflect his consistent commitment to innovation, patient safety, and education, solidifying his reputation as a respected leader in medical physics and radiation oncology.

Publication Top Notes

• AAPM TG report 312: Acceptance testing, commissioning, and periodic quality assurance of ion chamber and diode detector arrays — 2025

• Dosimetric characterization of a new surface-conforming electron MLC prototype — 2024 — 1 citation

• Monte Carlo modeling of the Elekta Versa HD and patient dose calculation with EGSnrc/BEAMnrc — 2022 — 5 citations

• Erratum to: Report of AAPM Task Group 219 on independent calculation-based dose/MU verification for IMRT — 2021

• Artificial intelligence based deconvolving on megavoltage photon beam profiles for radiotherapy applications — 2022

• A customizable aluminum compensator system for total body irradiation — 2021

Conclusion

Dr. Sotirios Stathakis’s career represents a remarkable combination of academic excellence, clinical innovation, and professional leadership. His work has transformed multiple aspects of radiation oncology, from enhancing treatment planning accuracy to implementing robust quality assurance protocols that safeguard patient outcomes. With a strong foundation in education from top institutions across Canada, the United Kingdom, and Greece, coupled with his leadership roles in the United States, he exemplifies the global nature of medical physics. His research interests and skills reflect both scientific rigor and compassion, as he continually integrates patient-centered approaches into his innovations. Recognized internationally through awards, honors, and professional certifications, Dr. Stathakis has established himself as a trusted authority in his field. His mentorship of students and collaboration with clinicians ensure that his influence extends beyond his individual achievements, shaping the future of cancer care. Looking ahead, his engagement with artificial intelligence, wearable technology, and advanced radiotherapy models positions him to make further groundbreaking contributions. In sum, Dr. Stathakis embodies the qualities of a dedicated researcher, educator, and clinician, making him not only a leader in medical physics but also a driving force in advancing the fight against cancer globally.