Tag: Molecular Science Award

Xiumin Wang | Molecular Biology | Women Researcher Award

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Prof. Dr. Xiumin Wang | Molecular Biology | Women Researcher Award

Researcher at Feed Research Institute, Chinese Academy of Agricultural Sciences, China

Dr. Wang Xiumin is a distinguished researcher currently serving at the Institute of Feed Research, Chinese Academy of Agricultural Sciences (CAAS). With a profound academic background and extensive research experience in the field of plant pathology and microbial resistance, Dr. Wang has become a leading figure in her field. Over her career, she has focused on microbial resistance, antibacterial peptides, and the development of therapeutic strategies to combat infectious diseases, especially those involving multi-drug resistant pathogens. Dr. Wang’s work has been instrumental in bridging the gap between fundamental microbiology and applied agricultural practices, contributing to the development of feed-related solutions and sustainable agricultural practices. Her research is widely recognized through numerous publications in prestigious scientific journals, where she has co-authored over 80 papers.

Professional Profile

Education:

Dr. Wang Xiumin obtained her Ph.D. in Plant Pathology from Northwest Agriculture & Forestry University in 2006, after completing her Master’s and Bachelor’s degrees at the same institution in 2003 and 2000, respectively. Her academic training equipped her with in-depth knowledge in plant protection and pathology, laying a strong foundation for her career in agricultural sciences and microbiology. Her academic journey enabled her to focus on plant diseases, microbiology, and biotechnology, advancing her research in combating bacterial resistance in agricultural systems.

Professional Experience:

Dr. Wang Xiumin has accumulated extensive professional experience across various prestigious institutions. From 2006 to 2009, she worked as a Postdoctoral Fellow at Beijing Forestry University, engaging in critical research in plant pathology. Between 2009 and 2013, she served as an Assistant Researcher at the Feed Research Institute of CAAS. Since 2013, she has held the position of Associate Researcher at the same institute. In 2019-2020, she visited the School of Chemistry and Molecular Biosciences at the University of Queensland, further enhancing her expertise in molecular biosciences and plant pathology. Throughout her career, Dr. Wang has continually advanced her research while mentoring emerging scientists in her field.

Research Interests:

Dr. Wang’s research interests lie at the intersection of microbial resistance, plant pathology, and feed-related research. Her work primarily focuses on antibacterial peptides, microbial resistance mechanisms, and the development of therapeutic proteins and peptides. She has also contributed to studies on food safety, including the detoxification of mycotoxins, and has explored the therapeutic potential of marine peptides for bacterial infections. Dr. Wang’s research in microbial resistance and peptide-based therapeutics is crucial for advancing sustainable agricultural and clinical practices, particularly in the context of combating drug-resistant pathogens in both animals and humans.

Research Skills:

Dr. Wang Xiumin is highly skilled in a variety of research techniques including molecular biology, microbiology, and biotechnology. She has experience in the design and application of antibacterial peptides, the isolation and characterization of bioactive compounds, and the assessment of microbial resistance mechanisms. Her expertise also extends to advanced techniques in molecular cloning, protein expression, and peptide synthesis. Additionally, Dr. Wang is adept at using in vitro and in vivo models to study the effects of therapeutic peptides and other compounds on microbial infections. Her diverse skill set has been pivotal in advancing her research projects and making significant contributions to agricultural and health sciences.

Awards and Honors:

Dr. Wang Xiumin has received several accolades for her outstanding contributions to the field of plant pathology and microbiology. She has been recognized for her innovative research in microbial resistance and peptide-based therapeutics, receiving awards from various scientific and agricultural bodies in China. Her significant publications in high-impact journals such as Science of the Total Environment, Journal of Medicinal Chemistry, and Food Chemistry have cemented her reputation as a leading researcher in her field. Additionally, her collaborative work with international research institutes has earned her several fellowships, including her research visit to the University of Queensland, further acknowledging her impact on global agricultural science and medical microbiology.

Conclusion

Dr. Wang Xiumin demonstrates a strong and well-rounded research profile, with impressive publications and a proven ability to address complex issues in plant pathology and antimicrobial resistance. His work is highly relevant and impactful in agricultural and biomedical fields. His contributions place him as a strong candidate for the Excellence in Research Award. Expanding his industry collaborations and mentoring roles would elevate his profile further, making him an even more influential figure in his field.

Publication Top Notes

  1. Application of Lactobacillus plantarum and Pediococcus lactis on Lipid Metabolism, Anti-Inflammatory, and Fecal Microbiota in Cats
    • Authors: Shukun Liang, Xinshu Gu, Jintao Sun, Xiumin Wang, Hui Tao, Zhenlong Wang, Yougang Zhong, Jinquan Wang, Bing Han
    • Year: 2024
    • DOI: 10.3390/microorganisms12122446
  2. Application of Network Pharmacology, Molecular Docking, and In Vitro Experimental Evaluation to Decipher the Anti-Inflammatory Mechanisms of Cirsium japonicum
    • Authors: Jiaxue Wang, Hui Tao, Zhenlong Wang, Wei An, Ya Zhao, Bing Han, Jinquan Wang, Xiuzhu Sun, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/app14219687
  3. Simultaneous Degradation of AFB1 and ZEN by CotA Laccase from Bacillus subtilis ZJ-2019-1 in the Mediator-Assisted or Immobilization System
    • Authors: Boquan Gao, Wei An, Jianwen Wu, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Zhenlong Wang, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/toxins16100445
  4. Allergies to Allergens from Cats and Dogs: A Review and Update on Sources, Pathogenesis, and Strategies
    • Authors: Wei An, Ting Li, Xinya Tian, Xiaoxin Fu, Chunxiao Li, Zhenlong Wang, Jinquan Wang, Xiumin Wang
    • Year: 2024
    • DOI: 10.3390/ijms251910520
  5. Bacillus subtilis Simultaneously Detoxified Aflatoxin B1 and Zearalenone
    • Authors: Jianwen Wu, Zhenlong Wang, Wei An, Boquan Gao, Chunxiao Li, Bing Han, Hui Tao, Jinquan Wang, Xiumin Wang, Huanrong Li
    • Year: 2024
    • DOI: 10.3390/app14041589
  6. The Effect of Lactobacillus plantarum on the Fecal Microbiota, Short Chain Fatty Acids, Odorous Substances, and Blood Biochemical Indices of Cats
    • Authors: Bing Han, Shukun Liang, Jintao Sun, Hui Tao, Zhenlong Wang, Baosheng Liu, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2024
    • DOI: 10.3390/microorganisms12010091
  7. Comparison Study of Two Fumonisin-Degrading Enzymes for Detoxification in Piglets
    • Authors: Zhenlong Wang, Zonghao Lv, Tibor Czabany, Veronika Nagl, Rudolf Krska, Xiumin Wang, Bing Han, Hui Tao, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/toxins16010003
  8. The Effect of Duck Bile Acid Extract on the Fecal Microbiota, Short Chain Fatty Acids, Fat Digestibility and Blood Biochemical Indices in Cats
    • Authors: Bing Han, Peng Zhao, Shukun Liang, Zhenlong Wang, Hui Tao, Xiumin Wang, Jie Liu, Jinquan Wang
    • Year: 2023
    • DOI: 10.3390/app13179713
  9. A Screening Model of Antibacterial Agents Based on Escherichia coli Cell-Division Protein
    • Authors: Qiuyu Fan, Jianwen Wu, Bolin Xi, Chunxiao Li, Xiumin Wang, Huanrong Li
    • Year: 2023
    • DOI: 10.3390/app13074493
  10. Mini-Review: Antibiotic-Resistant Escherichia coli from Farm Animal-Associated Sources
    • Authors: ChunMing Xu, Lingqiang Kong, Yonghong Liao, Yuan Tian, Qi Wu, Haosi Liu, Xiumin Wang
    • Year: 2022
    • DOI: 10.3390/antibiotics11111535

 

Mahdieh Mondanizadeh | Molecular Medicine | Best Researcher Award

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Dr. Mahdieh Mondanizadeh | Molecular Medicine | Best Researcher Award

Department of Biotechnology and Molecular Medicine, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.

Dr. Mahdieh Mondanizadeh is an Associate Professor of Molecular Medicine at Arak University of Medical Sciences, Iran. With a Ph.D. in Medical Molecular Medicine from Hamedan University of Medical Sciences, her research focuses on the role of microRNAs in cancer diagnosis, treatment, and neurological disorders. Dr. Mondanizadeh has led numerous research projects and thesis works, contributing significantly to the understanding of miRNAs in various diseases, including gastric cancer, glioma, and spinal cord injuries. Her work is widely published in esteemed journals, highlighting her expertise in molecular biology and her commitment to advancing medical science. Dr. Mondanizadeh’s research has practical implications, such as the development of non-invasive diagnostic methods for cancer and the exploration of targeted therapies. Her international exposure, including a visit to the University of Adelaide, further underscores her global perspective and dedication to collaborative research.

Profile
Education

Dr. Mahdieh Mondanizadeh is a highly qualified academic and researcher in the field of molecular medicine. She earned her Ph.D. in Medical Molecular Medicine from Hamedan University of Medical Sciences, Hamedan, Iran, where she conducted significant research from 2010 to 2014. Her doctoral thesis focused on evaluating the effect of miR-124 on transcription factors involved in the proliferation and differentiation of neuronal cells. Prior to her Ph.D., Dr. Mondanizadeh completed her M.Sc. in Medical Microbiology at Qom Islamic Azad University, Qom, Iran, from 2005 to 2007, further solidifying her foundation in microbiological research. She also holds a B.Sc. in Microbiology from Arak Azad University, Arak, Iran, which she completed between 2000 and 2004. In 2012, Dr. Mondanizadeh expanded her expertise through a visitorship at the University of Adelaide, Australia, enriching her research experience and international collaboration skills.

Professional Experience

Dr. Mahdieh Mondanizadeh is an Associate Professor of Molecular Medicine at the Department of Biotechnology, Arak University of Medical Sciences, Iran. Since joining the institution in 2015, she has made significant contributions to the field of molecular medicine, focusing on the role of microRNAs in cancer diagnosis and treatment. Dr. Mondanizadeh has successfully led numerous research projects, including the development of novel diagnostic assays and the investigation of miRNA-related gene expression in various diseases. Her expertise extends to the study of molecular pathways in cancer, spinal cord injuries, and neurodegenerative diseases. Additionally, she has collaborated with international researchers and published extensively in high-impact journals. Her work is recognized for its innovation and potential to influence future medical treatments, making her a respected figure in the scientific community.

Research Interest

Mahdieh Mondanizadeh’s research interests are deeply rooted in molecular medicine, with a particular focus on the role of microRNAs (miRNAs) in various human diseases. Her work extensively explores the regulatory functions of miRNAs in cancer, neurological disorders, and infectious diseases, aiming to uncover their potential as diagnostic biomarkers and therapeutic targets. Mondanizadeh is especially interested in the molecular mechanisms underlying cancer progression, including the role of miRNAs in signal transduction pathways and gene expression regulation. Her research also extends to the study of miRNA involvement in spinal cord injuries, neurodegenerative diseases, and reproductive health issues. Additionally, she investigates the therapeutic potential of natural compounds and their effects on miRNA expression and cancer treatment. Through her research, Mondanizadeh contributes to the development of novel diagnostic tools and targeted therapies, advancing the field of personalized medicine.

Research Skills

Mahdieh Mondanizadeh is a highly skilled researcher with extensive expertise in molecular medicine and microbiology. Her research skills are demonstrated through her successful management of numerous projects focused on the role of microRNAs in cancer, neurodegenerative diseases, and infectious diseases. She excels in designing and conducting complex experiments, particularly those involving gene expression analysis, miRNA profiling, and the development of diagnostic assays. Her proficiency in molecular techniques such as real-time PCR, immunohistochemistry, and cell culture is complemented by her strong analytical abilities, allowing her to interpret data with precision and contribute to high-impact publications. Additionally, her collaborative approach and leadership in multidisciplinary research projects highlight her ability to integrate various scientific disciplines. Mondanizadeh’s commitment to advancing molecular medicine is further evidenced by her active participation in grant writing and project management, ensuring the successful completion and dissemination of her research findings.

Awards and Recognition

Dr. Mahdieh Mondanizadeh has garnered significant recognition for her impactful contributions to the field of molecular medicine and biotechnology. As an Associate Professor at Arak University of Medical Sciences, she has received multiple research grants and led numerous projects focusing on the role of microRNAs in various diseases, particularly cancer. Her innovative work in non-invasive cancer diagnostics and therapeutic strategies has earned her acclaim both nationally and internationally. Dr. Mondanizadeh has published extensively in high-impact journals, highlighting her research excellence and commitment to advancing medical science. She has also been invited to present her findings at prestigious conferences, further cementing her reputation as a leading researcher in her field. Her dedication to mentoring students and fostering a collaborative research environment has also been recognized, making her a respected figure in the academic community.

Conclusion

Mahdieh Mondanizadeh is a strong candidate for the Best Researcher Award due to her extensive research achievements, leadership in scientific projects, and significant contributions to the understanding of molecular mechanisms in disease. Enhancing the application and impact of her research findings and expanding her international collaborations could further bolster her candidacy. Overall, her work positions her as a deserving contender for this prestigious recognition.

Publications Top Notes

  1. MiRNAs related in signaling pathways of women’s reproductive diseases: an overview
    • Authors: M. Bagheri, B. Khansarinejad, M. Mondanizadeh, M. Azimi, S. Alavi
    • Year: 2024
  2. A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle-related genes and miRNAs in triple-negative breast cancer cells
    • Authors: A. Tafti, S. Shojaei, H. Zali, S. Mohammadi-Yeganeh, M. Mondanizadeh
    • Year: 2023
    • Citations: 2
  3. Assessment of efficacy of carboxytherapy in management of skin aging through evaluation of gene expression profile: a 2-split randomized clinical trial
    • Authors: N. Bagherani, A. Firooz, A. Ghanadan, M. Mondanizadeh, G. Tavoosidana
    • Year: 2023
  4. Hsa-miR-15b-5p/miR-195-5p Controls Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells Through Regulating Indian Hedgehog Expression
    • Authors: S. Harimi, B. Khansarinejad, F. Fesahat, M. Mondanizadeh
    • Year: 2023
  5. Optimizing a Calorimetric Method for Quantitative Assessment of Alkaline Phosphatase to confirm the Osteogenic Differentiation of Mesenchymal Stem Cell
    • Authors: S. Harimi, F. Zare, F. Fesahat, M. Mondanizadeh
    • Year: 2023
  6. The role of microRNAs in diseases and related signaling pathways
    • Authors: A. Vaghf, B. Khansarinejad, E. Ghaznavi-Rad, M. Mondanizadeh
    • Year: 2022
    • Citations: 9
  7. Low Frequency of Adenovirus, Rotavirus, and Norovirus in Pediatric Diarrheal Samples from Central Iran
    • Authors: E. Abbasi, M. Mondanizadeh, A. van Belkum, E. Ghaznavi-Rad
    • Year: 2022
    • Citations: 3
  8. The role of miRNAs as a big master regulator of signaling pathways involved in lymphoblastic leukemia
    • Authors: M. Bagheri, P.Z. Sarabi, M. Mondanizadeh
    • Year: 2022
    • Citations: 3
  9. A Review of the Function of Circulating Cell Free miRNAs as Promising Biomarkers in Cancer Diagnosis, Treatment, and Metastasis
    • Authors: M. Zand, M. Mondanizadeh
    • Year: 2022
  10. Pap Smear miR-92a-5p and miR-155-5p as Potential Diagnostic Biomarkers of Squamous Intraepithelial Cervical Cancer
    • Authors: T. Azimi, M. Paryan, M. Mondanizadeh, H. Sarmadian, A. Zamani
    • Year: 2021
    • Citations: 8

 

Jaafar Abduo | Prosthodontics | Best Researcher Award

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Assoc Prof Dr. Jaafar Abduo | Prosthodontics | Best Researcher Award

Prosthodontist at Melbourne Dental School, Australia.

Dr. Jaafar Abduo is an Associate Professor of Prosthodontics at Melbourne Dental School, University of Melbourne. He holds a PhD from the University of Western Australia and has extensive experience in clinical dentistry. His research focuses on digital workflows, implant prosthodontics, and the evaluation of modern dental manufacturing techniques. Dr. Abduo has published over 90 peer-reviewed papers and has a significant impact on the field, with an h-index of 30 and more than 4,600 citations. He collaborates with leading dental companies and has been awarded multiple national and international grants. Additionally, he serves on various academic and professional committees, contributing to research ethics, curriculum development, and continuing education. Dr. Abduo’s work has been presented at major international conferences, and his innovations have influenced both academic research and clinical practices in prosthodontics globally.

Profile
Education

Dr. Jaafar Abduo’s educational background is distinguished by his extensive training in dentistry and prosthodontics. He earned his Doctor of Philosophy (PhD) by publication from the University of Western Australia in 2016, which reflects his significant contributions to dental research. Prior to this, he completed the Doctor of Clinical Dentistry in Prosthodontics (DClinDent) at the University of Otago, Dunedin, New Zealand, in 2010, underscoring his specialized expertise in prosthodontics. His journey began with a Bachelor of Dental Surgery with credit from the University of Otago in 2004. Additionally, he achieved Membership of the Royal Australasian College of Dental Surgeons in Prosthodontics (MRACDS Pros) through examination in Sydney, Australia, in 2011. This robust educational foundation has equipped Dr. Abduo with the knowledge and skills necessary to advance the field of dental prosthetics.

Professional Experience

Dr. Jaafar Abduo is an accomplished prosthodontist and Associate Professor at the Melbourne Dental School, University of Melbourne. Since January 2020, he has held the position of Associate Professor (Level D) in Prosthodontics, where he also serves as the Convenor for the Doctor of Clinical Dentistry (Prosthodontics) program and the Postgraduate Diploma in Clinical Dentistry (Implants). Dr. Abduo’s career at the Melbourne Dental School began in 2013 as a Senior Lecturer (Level C) in Prosthodontics. Alongside his academic roles, he has been a practicing specialist prosthodontist in private practice since 2011. Dr. Abduo’s expertise spans removable prosthodontics, complex rehabilitation, and implant prosthodontics, and he is actively involved in both teaching and research. His work is well-regarded, with numerous peer-reviewed publications and significant contributions to advancing dental education and clinical practice.

Research Interest

Dr. Jaafar Abduo’s research interests are centered around advancing prosthodontics, with a particular focus on digital dentistry and modern manufacturing techniques. He explores the development and evaluation of digital workflows for diagnostics, conventional, removable, and implant prosthodontics, aiming to improve accuracy and efficiency in dental treatments. His work also includes randomized controlled trials to assess the clinical outcomes of materials such as monolithic zirconia and metal-ceramic implant crowns. Additionally, Dr. Abduo is interested in optimizing digital scanning methods for natural teeth, soft tissue, and implants. His biomechanical studies on implant and natural tooth comparisons, along with his research on the durability of dental prosthetics, contribute to enhancing the quality and longevity of dental restorations. Through his research, Dr. Abduo seeks to bridge the gap between clinical practice and technological advancements, ultimately improving patient outcomes in prosthodontics.

Research Skills

Dr. Jaafar Abduo possesses a comprehensive set of research skills that have greatly contributed to the field of prosthodontics. His expertise lies in digital dentistry, particularly in developing and optimizing digital workflows for various prosthodontic procedures, including implant and removable prosthodontics. He is proficient in conducting randomized controlled trials and biomechanical evaluations, ensuring the clinical efficacy and durability of dental materials and techniques. Dr. Abduo’s collaboration with industry leaders showcases his ability to bridge academic research with practical applications, enhancing dental treatment outcomes. His supervisory experience, guiding numerous Doctor of Clinical Dentistry and postgraduate students, demonstrates his mentorship skills and commitment to advancing dental education. Additionally, Dr. Abduo has secured multiple research grants, highlighting his capability in securing funding and managing large-scale projects. His strong publication record, with a high h-index and numerous citations, underscores his ability to disseminate research findings effectively and contribute to the broader scientific community.

Awards and Recognition

Dr. Abduo has received several prestigious awards and grants, including the F. A. Kernott Early Career Researcher Award and various grants from the Australian Dental Research Foundation and international sources. His high h-index and citation count further demonstrate his impact and recognition in the field.

Conclusion

Dr. Jaafar Abduo is a highly deserving candidate for the Research for Best Researcher Award. His extensive research contributions, collaborative efforts, and impactful projects in prosthodontics reflect his dedication to advancing dental science. His work has both national and international significance, making him a prominent figure in the field of dental research.

Publications Top Notes

  • “Muscle and joint mechanics during maximum force biting following total temporomandibular joint replacement surgery”
    • Authors: Woodford, S.C., Robinson, D.L., Abduo, J., Lee, P.V.S., Ackland, D.C.
    • Year: 2024
    • Citations: 0
  • “Effect of prefabricated immediate interim prosthesis design and insertion workflow on seating accuracy on implants placed via static computer-assisted implant surgery: A cross-sectional in vitro study”
    • Authors: Abduo, J., Lau, D.
    • Year: 2024
    • Citations: 0
  • “Influence of Implant Adjacent Teeth on the Accuracy of Digital Impression”
    • Authors: Abduo, J., El-Haddad, H.
    • Year: 2024
    • Citations: 0
  • “Seating accuracy of removable partial denture frameworks fabricated by different digital workflows in comparison to conventional workflow”
    • Authors: Korkes, A., Jomaa, J., Kavouris, A., Law, K.H.J., Abduo, J.
    • Year: 2024
    • Citations: 0
  • “Effect of pilot-guided implant placement concept on the accuracy of osteotomy preparation and implant placement”
    • Authors: Sharma, S., Tan, E., Tran, B., Teo, J., Abduo, J.
    • Year: 2024
    • Citations: 0
  • “The Effect of Various Lasers on the Bond Strength Between Orthodontic Brackets and Dental Ceramics: A Systematic Review and Meta-Analysis”
    • Authors: Mosaddad, S.A., Abduo, J., Zakizade, M., Tebyaniyan, H., Hussain, A.
    • Year: 2024
    • Citations: 2
  • “Accuracy of Static Computer-Assisted Implant Placement in Posterior Edentulous Areas with Different Levels of Tooth-Support by Novice Clinicians”
    • Authors: Abduo, J., Lau, D.
    • Year: 2023
    • Citations: 0
  • “Kinematics of the jaw following total temporomandibular joint replacement surgery”
    • Authors: Woodford, S.C., Robinson, D.L., Abduo, J., Lee, P.V.S., Ackland, D.C.
    • Year: 2023
    • Citations: 3
  • “Marginal Accuracy of Monolithic and Veneered Zirconia Crowns Fabricated by Conventional and Digital Workflows”
    • Authors: Abduo, J., Ho, G., Centorame, A., Le, P., Ngo, C.
    • Year: 2023
    • Citations: 3
  • “Measuring tooth movement with treatment using the Dahl principle: An observational study”
    • Authors: Bhai, K., Judge, R., Abduo, J., Palamara, J.
    • Year: 2023
    • Citations: 1

Mariela Gironacci | Molecular Biology | Best Researcher Award

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Prof. Mariela Gironacci | Molecular Biology | Best Researcher Award

Professor at University of Buenos Aires , Argentina.

Dr. Mariela Mercedes Gironacci is a distinguished Associate Professor in the Department of Biological Chemistry at the School of Pharmacy and Biochemistry, Buenos Aires University. With a Ph.D. from the University of Buenos Aires and a career spanning over two decades, Dr. Gironacci has made significant contributions to hypertension research. Her work focuses on the Mas receptor and its role in anti-inflammatory and antihypertensive responses. She has led multiple research projects funded by CONICET and other national and international bodies. Dr. Gironacci has received numerous awards, including the Braun Menéndez Award and the Prof. Dr. Luis Moledo Award, recognizing her excellence in hypertension research. She is an active member of professional societies, serves on editorial boards, and has delivered invited lectures globally. Her research impact is evident in her extensive publications and her leadership in advancing our understanding of the renin-angiotensin system.

Profile
Education

Dr. Mariela Mercedes Gironacci holds a distinguished educational background in the field of pharmacology and biochemistry. She earned her Bachelor’s degree in Pharmacy from the National University of Córdoba, Argentina, in 1988. Building upon this foundation, she pursued advanced studies at the University of Buenos Aires, where she completed her Ph.D. in 1999. Her doctoral research contributed significantly to the understanding of the renin-angiotensin system, particularly in relation to hypertension. Dr. Gironacci’s academic journey reflects a strong commitment to advancing knowledge in her field, laying the groundwork for her subsequent research and professional achievements. Her education has equipped her with the expertise necessary to make substantial contributions to pharmacology and biochemistry, particularly in hypertension and cardiovascular research.

Professional Experience

Dr. Mariela Mercedes Gironacci is an esteemed Associate Professor in the Department of Biological Chemistry at the School of Pharmacy and Biochemistry, Buenos Aires University, where she has served since March 2023. Her academic career began as an Instructor in 1991, progressing to Assistant Professor (1996-2008) and then Associate Professor (2008-2023) before her current role. Concurrently, Dr. Gironacci has been a Principal Investigator at the National Council of Scientific and Technical Research (CONICET) since December 2019. Her research focuses on hypertension and cardiovascular health, particularly the Mas receptor’s role in antihypertensive responses. Her leadership extends to serving on various editorial boards, including Hypertension and the Journal of the Argentinian Society of Hypertension, and she has held significant positions in professional societies, including the Inter-American Society of Hypertension. Her extensive experience in teaching, research, and leadership underscores her significant contributions to the field.

Research Interest

Dr. Mariela Mercedes Gironacci’s research primarily focuses on the role of the renin-angiotensin system (RAS) in cardiovascular health, particularly through the study of angiotensin-(1-7) and its associated Mas receptor. Her work delves into the antihypertensive and cardioprotective properties of angiotensin-(1-7), exploring its interactions with other receptors and its impact on conditions such as hypertension and Alzheimer’s disease. Dr. Gironacci’s research also examines the receptor’s involvement in inflammatory responses and its potential therapeutic targets for hypertension and neurodegenerative disorders. She is engaged in elucidating the mechanisms behind Mas receptor trafficking and its role in regulating blood pressure and cardiac function. Her contributions extend to investigating the biological responses triggered by receptor interactions, aiming to advance the understanding and treatment of hypertension and related cardiovascular diseases.

Research Skills

Dr. Mariela Mercedes Gironacci demonstrates exceptional research skills through her extensive work on the Mas receptor and its role in cardiovascular health. Her expertise encompasses a deep understanding of receptor regulation and trafficking, particularly in relation to antihypertensive responses. Dr. Gironacci has led pioneering studies on the depressor axis of the renin-angiotensin system, focusing on the receptor Mas and its interactions with other receptors. Her ability to design and execute complex research projects is evident in her numerous high-impact publications and successful grant applications. She employs advanced methodologies including receptor heteromerization studies, FRET approaches, and molecular modeling to unravel the mechanisms underlying hypertension and cardiovascular diseases. Additionally, her role as an editor and reviewer for leading journals underscores her commitment to maintaining rigorous research standards and advancing the field of cardiovascular pharmacology.

Awards and Recognition

Dr. Gironacci has received numerous awards for her contributions to hypertension research, including prestigious recognitions such as the Braun Menendez Award, the Luis Moledo Award, and the Prof. Dr. C. Taquini Award. These accolades reflect her excellence in research and her impact on the field. Her recognition extends to both national and international levels, highlighting her standing as a leading researcher in her field.

Conclusion

Dr. Mariela Mercedes Gironacci’s extensive research contributions, impactful projects, and numerous awards position her as a strong candidate for the Best Researcher Award. Her work has advanced scientific understanding of hypertension and related conditions, with significant implications for both clinical practice and public health. Her dedication to research, collaborative efforts, and recognition by prestigious institutions underscore her outstanding achievements in the field.

Publications Top Notes

  1. Circulating angiotensin-(1-7) is decreased in patients with isolated nocturnal hypertension
    • Authors: J. Minetto, M.B. Cuello, F.P. Dominici, W.G. Espeche, M.M. Gironacci
    • Year: 2024
  2. Unraveling the crosstalk between renin-angiotensin system receptors
    • Authors: M.M. Gironacci, E. Bruna-Haupt
    • Year: 2024
  3. Valproate decreases transgenerationally blood pressure by affecting thyrotropin-releasing hormone promoter DNA methylation and gene expression in spontaneously hypertensive rat
    • Authors: M.S. Landa, M.L. Schuman, M. Aisicovich, S.I. García, C.J. Pirola
    • Year: 2024
  4. Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli
    • Authors: C. Berdasco, A. Pinto, M.G. Blake, J. Gironacci, J. Goldstein
    • Year: 2023
    • Citations: 1
  5. Effect of age on human ACE2 and ACE2-expressing alveolar type II cells levels
    • Authors: M.G. Silva, N.L. Falcoff, G.R. Corradi, M. Nuñez, M.M. Gironacci
    • Year: 2023
    • Citations: 12
  6. Mechanistic approaching study in COVID-19 patients treated with high doses of vitamin D
    • Authors: M.G. Silva, F. Inserra, J. Mariani, W. Manucha, M.M. Gironacci
    • Year: 2023
    • Citations: 1
  7. Mas receptor endocytosis and signaling in health and disease
    • Authors: N.L. Rukavina Mikusic, M.M. Gironacci
    • Year: 2023
  8. Plasmatic renin-angiotensin system in normotensive and hypertensive patients hospitalized with COVID-19
    • Authors: M.G. Silva, G.R. Corradi, J.I. Pérez Duhalde, W.G. Espeche, M.M. Gironacci
    • Year: 2022
    • Citations: 6
  9. Renin-angiotensin system blockade on angiotensin-converting enzyme 2 and TMPRSS2 in human type II pneumocytes
    • Authors: M.G. Silva, N.L. Falcoff, G.R. Corradi, G.R. Guman, M.M. Gironacci
    • Year: 2022
    • Citations: 4
  10. ACE2 internalization induced by a SARS-CoV-2 recombinant protein is modulated by angiotensin II type 1 and bradykinin 2 receptors
    • Authors: A.E. Portales, E.R. Mustafá, C.I. McCarthy, M. Perelló, J. Raingo
    • Year: 2022
    • Citations: 8