Perihan AKBAŞ | Microbiology | Best Researcher Award

Assist. Prof. Dr. Perihan AKBAŞ | Microbiology | Best Researcher Award

Ondokuz Mayıs University, Turkey

Dr. Perihan Akbaş is a distinguished microbiologist and academic at Ondokuz Mayıs University, Turkey, specializing in microbiology, biotechnology, and food microbiology. With a PhD in General Biology from Atatürk University and a strong foundation in biological sciences, she has built a remarkable career centered around the investigation of natural antimicrobial agents and microbial safety in foods. Over two decades, Dr. Akbaş has contributed extensively to scientific literature with numerous articles in international peer-reviewed journals, focusing on plant extracts, peptone production from insects, and microbial food safety. Her academic leadership is reflected through her advisory roles in postgraduate theses and participation in international scientific congresses. She has also authored chapters in scholarly books, further underlining her interdisciplinary expertise. Known for her rigorous scientific methodology and innovative research, Dr. Akbaş continues to play a key role in shaping future research in applied microbiology and forensic biotechnology.

Professional Profile

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Education

Dr. Perihan Akbaş began her academic journey with a Bachelor’s degree in Biology from Atatürk University, graduating in 2002. She earned her Master’s degree in Biology (with thesis) from Kafkas University in 2004, with a thesis focused on the investigation of E. coli O157:H7 in doner kebabs sold in Kars. In 2013, she completed her Ph.D. in General Biology at Atatürk University’s Institute of Science. Her doctoral thesis explored the use of the Locusta migratoria grasshopper as a microbial peptone source, supervised by Prof. Dr. Esabi Başaran Kurbanoğlu. Her academic training provided a strong basis in microbiology, food safety, and biotechnology, laying the groundwork for her diverse research portfolio. Her educational background spans microbiological analysis, natural antimicrobial agents, microbial growth media development, and environmental biology, which collectively shape her research focus in applied and forensic sciences.

Professional Experience 

Dr. Akbaş’s academic career spans various prestigious institutions. She served as Assistant Professor at Kafkas University between April 2014 and April 2022 in the Department of Medical Services and Techniques. Since April 2022, she has held the same title at Ondokuz Mayıs University’s School of Health Services, specifically in the Pathology Laboratory Techniques program. In addition to teaching, she contributed administratively as Deputy Director of the Karadeniz Advanced Technology Application and Research Center (2022–2024). Her experience extends to supervising graduate theses on emerging topics in forensic and medical sciences. She has led and participated in multiple national and international scientific conferences and has extensive experience in academic publishing, curriculum development, and student mentoring. Dr. Akbaş’s multidisciplinary approach integrates microbiology, biochemistry, and forensic science, reflecting her commitment to high-impact research and education.

Awards and Honors 

Dr. Perihan Akbaş is widely recognized for her academic excellence and research contributions. Though individual award details are not extensively listed, her scientific impact is evident through frequent citations, international publications, and invited presentations. Her works, especially those focused on antimicrobial agents derived from plants and microorganisms, have drawn attention in the scientific community. She has also contributed to several prestigious congresses as an oral presenter and co-author, indicating peer recognition. Additionally, she has co-authored chapters in international books published by reputable publishers, such as Serüven Yayınevi and Gece Kitaplığı. Her consistent output and mentorship of postgraduate research further reflect her academic leadership. Being a regular presenter at national and international conferences and having contributed to forensic and food microbiology literature, Dr. Akbaş is regarded as a reliable scientific voice in her domain.

Research Interests

Dr. Akbaş’s research focuses on microbiology, biotechnology, and food safety. Her primary interest lies in investigating the antimicrobial and antioxidant activities of natural plant extracts, such as Peganum harmala, Rumex patientia, and Hyoscyamus reticulatus. She explores their applications in treating microbial infections and as food preservatives. Another key area is food microbiology, specifically the detection of pathogens like E. coli O157:H7 and Salmonella spp. in meat products. She also delves into the biotechnological production of microbial peptones from unconventional sources like Locusta migratoria and the use of deep eutectic solvents for bioactive compound extraction. Dr. Akbaş integrates modern analytical techniques like GC-MS/MS and XRF into her work, linking biological efficacy with chemical composition. Her interdisciplinary approach merges microbiology, toxicology, and forensic science, making her research impactful for both clinical and food safety applications.

Research Skills 

Dr. Perihan Akbaş possesses extensive skills in experimental microbiology, including antimicrobial susceptibility testing, microbial culture techniques, and food safety assessment. She is proficient in biochemical analysis methods such as GC-MS/MS, X-ray fluorescence (XRF), and spectrophotometric assays. Her expertise also includes extraction of active compounds using classical solvents and advanced deep eutectic solvents. She has hands-on experience in developing and optimizing microbial growth media from alternative nitrogen sources. Dr. Akbaş is adept at statistical analysis of biological data, manuscript preparation, and interdisciplinary research design. Her work frequently bridges forensic, environmental, and food sciences. Additionally, she demonstrates strong supervisory skills, guiding MSc and PhD students in developing scientifically sound and ethically approved research. She actively participates in scientific writing, peer reviewing, and interdisciplinary collaboration, making her a versatile and impactful researcher.

Conclusion

Dr. Perihan Akbaş is a prominent academic whose interdisciplinary expertise spans microbiology, biotechnology, food safety, and forensic sciences. Her innovative research, dedication to academic mentorship, and continuous contributions to scientific literature make her a respected figure in the scientific community. Her ability to blend practical applications with fundamental research reflects her value as both a scientist and educator.

Publication Top Notes

  1. Akbaş P., Kaya E., Makav M., Yıldız G. (2023). Antimicrobial and antioxidant activities of Chenopodium album extracts.

  2. Kaya E., Akbaş P. (2023). Antimicrobial, antioxidant activities and fatty acid composition of Peganum harmala Seed.

  3. Akbaş P., Kurbanoğlu E.B. (2022). Locusta migratoria as a nitrogen source for microbial growth.

  4. Alkan H., Akbaş P., Durhan S., Öztürkler O. (2021). Antimicrobial activity of horseradish root.

  5. Kaya E., Akbaş P., et al. (2020). Fatty acid composition of Rumex patientia and antimicrobial activity.

  6. Akbaş P., Uslu H., et al. (2020). Antimicrobial and apoptotic activity of Hyoscyamus reticulatus.

  7. Akbaş P., Kaya E., et al. (2020). XRF and antibacterial characteristics of Hyoscyamus reticulatus seeds.

  8. Alkan H., Akbaş P., et al. (2017). Assertiveness level of health services vocational school students.

  9. Akbaş P., Gürsoy Kol Ö., et al. (2017). Antimicrobial and antioxidant activity of watermelon and seeds.

  10. Gürbüz A., Akbaş P. (2015). Antibiotic susceptibility of Pseudomonas aeruginosa from bovine lungs.

  11. Ulukanlı Z., Akbaş P., Tuzcu M. (2006). E. coli O157:H7 in doner kebabs in Kars.

  12. Elmali M., Ulukanlı Z., et al., Akbaş P. (2005). E. coli O157:H7 detection from ground beef in Turkey.

  13. Elmali M., Ulukanlı Z., et al., Akbaş P. (2005). Microbiological quality of beef doner kebabs in Turkey.

Jean-Michel Bolla | Immunology and Microbiology | Best Researcher Award

Dr. Jean-Michel Bolla | Immunology and Microbiology | Best Researcher Award

Dr. Jean Michel Bolla is a distinguished researcher specializing in microbiology, biochemistry, and antibiotic resistance. With over 30 years of experience, he has made significant contributions to understanding bacterial resistance mechanisms, particularly efflux-mediated resistance in Gram-negative bacteria. As the Director of Research at Inserm U-1261, he has led pioneering studies in bacterial physiology and virulence, as well as the development of screening platforms for antibiotic-resistant bacteria. His leadership in the Bac-Screen platform, which enables high-throughput screening of antimicrobial compounds, highlights his commitment to innovative research. Dr. Bolla has supervised multiple PhD students and postdoctoral researchers, securing major research funding from national and international agencies. His work has been recognized through invited talks at international conferences and a patent related to diagnostic tools for antibiotic resistance. Additionally, he has contributed significantly to academia through teaching roles at Aix-Marseille Université and Université de Corse. His research continues to shape the field of antimicrobial resistance, addressing one of the most pressing global health challenges. Through his expertise, leadership, and dedication to scientific advancement, Dr. Bolla has established himself as a leading figure in microbiology and antibiotic resistance research.

Professional Profile

Education

Dr. Jean Michel Bolla holds a PhD in Biochemistry and Molecular Biology from UPR9027 CNRS, Marseille, awarded in 1990. His doctoral research focused on protein export and assembly in Escherichia coli, conducted under the supervision of Dr. JM Pagès. Following his PhD, he pursued a postdoctoral fellowship at Inserm-APHP, Paris, where he worked on iron starvation responses in Listeria monocytogenes under Dr. P. Berche. His advanced training includes specialization in Campylobacter porins at the Laboratory Centre for Disease Control in Ottawa and Winnipeg, Canada in 1997 and 1998. In 2001, he obtained his Habilitation à Diriger des Recherches (HDR) from the Faculty of Medicine, Timone, Marseille, enabling him to supervise doctoral research. His extensive academic training has provided him with a strong foundation in molecular microbiology, biochemistry, and antibiotic resistance. Through continuous education and research, Dr. Bolla has developed a deep understanding of bacterial physiology, antimicrobial resistance mechanisms, and drug discovery. His educational background has been instrumental in shaping his career as a leading researcher in microbiology and antibiotic resistance, allowing him to contribute groundbreaking insights to the field.

Professional Experience

Dr. Jean Michel Bolla has had an illustrious career in research, spanning over three decades. He began as a postdoctoral researcher at Inserm-APHP, Paris, before joining Inserm as a Chargé de Recherche in 1992. Over the years, he advanced within Inserm, holding key research positions, and became Director of Research at U-1261 in 2018. He has led major research initiatives, including the establishment of the Bac-Screen platform, a high-throughput screening system for antibiotic resistance studies. From 2007 to 2011, he also served as an Associate Professor at the Université de Corse, where he contributed significantly to teaching and student mentorship. Throughout his career, Dr. Bolla has supervised seven PhD students and three postdoctoral researchers, demonstrating his commitment to training future scientists. He has been an invited speaker at multiple international conferences, sharing his expertise in antibiotic resistance. His ability to secure major research funding, including grants from CNRS, ANR, and FEAMPA, underscores his impact in the field. His leadership roles at Inserm and collaborations with various research institutions have solidified his reputation as an expert in microbiology and antibiotic resistance.

Research Interest

Dr. Jean Michel Bolla’s research primarily focuses on antibiotic resistance mechanisms, with a particular emphasis on efflux-mediated resistance in Gram-negative bacteria. His work explores the physiology and virulence of bacterial pathogens, including Campylobacter jejuni and Listeria monocytogenes. He is deeply involved in drug discovery and screening technologies, having developed the Bac-Screen platform to identify novel antimicrobial compounds and assess their mechanisms of action. His research also extends to bacterial membrane permeability, studying how bacterial outer membrane porins influence antibiotic uptake and resistance. More recently, he has been engaged in synthetic antibacterial polymer development for therapeutic applications. His work contributes to understanding multidrug resistance mechanisms, a major global health challenge, and seeks innovative solutions to combat bacterial infections. Additionally, he collaborates on projects involving diagnostic tools for detecting antimicrobial resistance, aiming to improve early detection and treatment strategies. Through his research, Dr. Bolla strives to bridge the gap between basic microbiology and clinical applications, working towards the development of effective antimicrobial strategies to tackle the increasing threat of drug-resistant bacteria worldwide.

Research Skills

Dr. Jean Michel Bolla possesses a diverse range of research skills, with expertise in molecular microbiology, biochemistry, and antimicrobial resistance. He has extensive experience in protein purification, bacterial physiology studies, and genetic manipulation of bacterial pathogens. His work in high-throughput screening techniques has been pivotal in identifying new inhibitors for efflux pumps in Gram-negative bacteria. He is proficient in drug discovery methodologies, including antibiotic susceptibility testing, mode-of-action studies, and bacterial membrane permeability analysis. Additionally, he has expertise in structural and functional analysis of bacterial outer membrane proteins, which play a crucial role in drug resistance. Dr. Bolla is also skilled in cell culture techniques, bioinformatics, and statistical analysis for interpreting large-scale screening data. His ability to secure major research funding highlights his competence in grant writing and project management. Furthermore, his teaching and mentorship experience demonstrate his ability to train and guide students in advanced microbiology research techniques. His research skills make him a valuable asset in the fight against antimicrobial resistance, as he continues to develop innovative solutions to combat bacterial infections.

Awards and Honors

Dr. Jean Michel Bolla has been recognized for his outstanding contributions to microbiology and antibiotic resistance research. In 2007, he was awarded the Inserm-Université Interface Contract, acknowledging his excellence in research and academic collaboration. His work in antimicrobial resistance has also been recognized through significant research grants from CNRS, ANR, and FEAMPA, underscoring the impact of his studies in drug discovery and bacterial resistance mechanisms. In 2019, his Bac-Screen platform was designated an Aix-Marseille University Technological Platform, a prestigious recognition that was renewed in 2023 for its critical role in antibiotic resistance research. His contributions to the field have also led to an international patent (WO 2023/139263 A1) for a diagnostic tool to detect drug resistance. Additionally, he has been an invited speaker at leading scientific conferences, including GRS-GRC Multidrug Efflux Systems and The 3rd International Electronic Conference on Antibiotics. His expertise and dedication to advancing microbial research have positioned him as a leading scientist in his field, earning him widespread recognition and respect.

Conclusion

Dr. Jean Michel Bolla is a highly accomplished microbiologist with a strong research background in antibiotic resistance and bacterial physiology. His contributions to understanding efflux-mediated resistance in Gram-negative bacteria have had a profound impact on the field. As Director of Research at Inserm U-1261, he has demonstrated exceptional leadership, securing major research funding and spearheading innovative screening platforms for antimicrobial resistance studies. His dedication to mentoring PhD students and postdoctoral researchers underscores his commitment to advancing scientific knowledge. Through his numerous research projects, international collaborations, and conference presentations, he continues to make significant strides in addressing the global challenge of antibiotic resistance. His patent for a diagnostic tool in antimicrobial resistance showcases his ability to translate research into real-world applications. Recognized through awards and honors, Dr. Bolla is a leading expert in microbiology and antimicrobial resistance. His work has positioned him as a key figure in drug discovery and bacterial resistance research, making him a strong contender for the Best Researcher Award. His career is a testament to scientific excellence, innovation, and dedication to global health challenges.

Publications Top Notes

  1. Title: RND Efflux Pump Induction: A Crucial Network Unveiling Adaptive Antibiotic Resistance Mechanisms of Gram-Negative Bacteria
    Authors: M. Novelli, Marine; J.M. Bolla, Jean Michel
    Year: 2024
    Citations: 5

  2. Title: Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities
    Authors: A. Di Maio, Attilio; H. Olleik, Hamza; É. Courvoisier-Dezord, Élise; M. Maresca, Marc; M. Robin, Maxime
    Year: 2024
    Citations: 1

  3. Title: Antitubercular potential and pH-driven mode of action of salicylic acid derivatives
    Authors: J. Laudouze, Janïs; T. Francis, Thomas; E. Forest, Emma; P. Santucci, Pierre; J.F. Cavalier, Jean-François
    Year: 2024

  4. Title: Synthesis and antimicrobial testing of 5-fluorouracil derivatives
    Authors: M.U. Patil, Mrunal Unmesh; S. Krykun, Serhii; F. Garzino, Frédéric; J.M. Bolla, Jean Michel; M. Camplo, Michel
    Year: 2023
    Citations: 5

  5. Title: The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence
    Authors: G. Wang, Gang; J.M. Brunel, Jean Michel; M. Preusse, Matthias; J.M. Bolla, Jean Michel; F. van Bambeke, Francoise
    Year: 2022
    Citations: 11

  6. Title: An Original and Efficient Antibiotic Adjuvant Strategy to Enhance the Activity of Macrolide Antibiotics against Gram-Negative Resistant Strains
    Authors: A. Troudi, Azza; J.M. Bolla, Jean Michel; N. Klibi, Naouel; J.M. Brunel, Jean Michel
    Year: 2022
    Citations: 4

  7. Title: The polyamino-isoprenyl potentiator NV716 revives disused antibiotics against Gram-negative bacteria in broth, infected monocytes, or biofilms, by disturbing the barrier effect of their outer membrane
    Authors: G. Wang, Gang; J.M. Brunel, Jean Michel; H. Rodríguez-Villalobos, Héctor; J.M. Bolla, Jean Michel; F. van Bambeke, Francoise
    Year: 2022
    Citations: 6

  8. Title: Nanoarchitectonics of Electrically Activable Phosphonium Self-Assembled Monolayers to Efficiently Kill and Tackle Bacterial Infections on Demand
    Authors: S. Carrara, Serena; F. Rouvier, Florent; S. Auditto, Sanjana; J.M. Bolla, Jean Michel; J.M. Raimundo, Jean Manuel
    Year: 2022
    Citations: 6